I had a Windows 2008 server that I was attempting to install the Symantec Endpoint client on, but the client would not install, and the following message was left in the event log:
Symantec Endpoint Protection (SEP) Installation fails with the following error “Symantec Endpoint Protection has detected that there are pending system changes that require a reboot. Please reboot the system and rerun the installation.”
I rebooted the server and then tried to install the client again, but the same error would appear.
I found that there was a registry entry that was giving me grief with the install, and here are the instructions that I used to fix the problem.
NOTE: If you are running Windows Vista look for this key – HKEY_LOCAL_MACHINE\SYSTEM\Current\ControlSet001\ControlSessionManager\PendingFileRenameOperations
* Thanks to Bill for this Windows Vista suggestion.